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GREGoRi Technology Integration Center (U01, Clinical Trials Optional)

HHS-NIH11 Forecasted FOR-HG-25-027

Description

The National Human Genome Research Institute (NHGRI) intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to renew the Genomics Research to Elucidate the Genetics of Rare Disease (GREGoR) program. The renewal, called GREGoR: Innovation (GREGoRi), seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this NOFO is to establish the GREGoRi Technology Integration Center (TechIC), which will enable the development of standards and best practices for applying new and emerging molecular methods in rare disease diagnosis. A major deliverable of the Center will be a multidimensional dataset that can be used for the development and benchmarking of novel tools and strategies that facilitate rare disease diagnosis. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in 2025 with an expected application due date in 2026. This NOFO will utilize the U01 activity code.
Funding Details
Award Floor
Not specified
Award Ceiling
Not specified
Total Estimated Funding
$3,000,000.00
Expected Awards
1
Key Dates
Posted
June 6, 2025
Closes
N/A
Archive Date
N/A
Agency Information
Agency Name
HHS-NIH11
Agency Code
HHS-NIH11
Funding Instrument
Other